The Bruker SkyScan 1276 µCT system is equipped with a 20-100 kV micro-focus X- ray source and a 11 Mp detector. It can apply variable magnification until reaching a high resolution with minimum pixel size below 3 Microns, enough to resolve structural details of the order of 5-6 Microns. The SkyScan is particularly indicated for longitudinal studies, because the radiation dose can be properly limited. The image analysis is performed with a dedicated software, InstaRecon, capable of providing fast reconstruction of 3D realistic images